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Blockade of adaptive defensive changes in cholesterol uptake and synthesis in AML by the addition of pravastatin to Idarubicin plus high dose Ara-C: A phase I study

Therefore, low glutathione levels can contribute to the inefficiency of methylation, creating a vicious cycle and furthering depleting ones glutathione levels

Gibson et al., 2018

Androgen receptor of rat penis is down-regulated by androgen

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Docetaxel/androgen deprivation therapy (ADT) combined with 150 mg/day of lycopene resulted in dose-limiting toxicity in 1 of 12 cases, establishing it as the MTD